B-type cyclins
E1539814
UNEXPLORED
B-type cyclins are regulatory proteins that control progression through mitosis in eukaryotic cells by activating cyclin-dependent kinases.
All labels observed (1)
| Label | Occurrences |
|---|---|
| B-type cyclins canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22516253 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: B-type cyclins Context triple: [Cdc28, formsComplexWith, B-type cyclins]
-
A.
Cdc28
Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
-
B.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
-
C.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
-
D.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
-
E.
Betz cells
Betz cells are large, pyramidal neurons in the primary motor cortex that play a key role in voluntary motor control by sending long axons to the spinal cord.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: B-type cyclins Target entity description: B-type cyclins are regulatory proteins that control progression through mitosis in eukaryotic cells by activating cyclin-dependent kinases.
-
A.
Cdc28
Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
-
B.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
-
C.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
-
D.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
-
E.
Betz cells
Betz cells are large, pyramidal neurons in the primary motor cortex that play a key role in voluntary motor control by sending long axons to the spinal cord.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.