MAFA transcription factor
E1365587
UNEXPLORED
MAFA transcription factor is a beta cell–specific transcription factor that plays a key role in regulating insulin gene expression and pancreatic islet function.
All labels observed (1)
| Label | Occurrences |
|---|---|
| MAFA transcription factor canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T19245357 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: MAFA transcription factor Context triple: [INS gene, regulatedBy, MAFA transcription factor]
-
A.
Sox2
Sox2 is a key transcription factor that maintains stem cell pluripotency and self-renewal and is widely used in cellular reprogramming.
-
B.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
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C.
CTCF
CTCF is a state prison facility in Colorado that houses incarcerated individuals under the jurisdiction of the Colorado Department of Corrections.
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D.
Oct3/4
Oct3/4 (also known as POU5F1) is a key transcription factor that maintains pluripotency and self-renewal in embryonic stem cells and is widely used in cellular reprogramming.
-
E.
MAF
MAF is the three-letter ISO 3166-1 alpha-3 country code assigned to the French overseas collectivity of Saint Martin in the Caribbean.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: MAFA transcription factor Target entity description: MAFA transcription factor is a beta cell–specific transcription factor that plays a key role in regulating insulin gene expression and pancreatic islet function.
-
A.
Sox2
Sox2 is a key transcription factor that maintains stem cell pluripotency and self-renewal and is widely used in cellular reprogramming.
-
B.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
-
C.
CTCF
CTCF is a state prison facility in Colorado that houses incarcerated individuals under the jurisdiction of the Colorado Department of Corrections.
-
D.
Oct3/4
Oct3/4 (also known as POU5F1) is a key transcription factor that maintains pluripotency and self-renewal in embryonic stem cells and is widely used in cellular reprogramming.
-
E.
MAF
MAF is the three-letter ISO 3166-1 alpha-3 country code assigned to the French overseas collectivity of Saint Martin in the Caribbean.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject linked to:
INS gene in humans