Loxo Oncology (acquired)

E133655

Loxo Oncology (acquired) is a biotechnology company focused on developing targeted cancer therapies, particularly for tumors driven by specific genetic alterations.

All labels observed (2)

Label Occurrences
Loxo Oncology 9
Loxo Oncology (acquired) canonical 1

How this entity was disambiguated

Statements (47)

Predicate Object
instanceOf biotechnology company ⓘ
oncology company ⓘ
acquiredBy Eli Lilly and Company ⓘ
acquisitionAnnouncedOn 2019-01-07 ⓘ
acquisitionCompletedOn 2019-02-15 ⓘ
acquisitionValueUSD 8000000000 ⓘ
coFounder David Hyman ⓘ
Joshua Bilenker ⓘ
Keith Flaherty ⓘ
collaborationPurpose development and commercialization of larotrectinib ⓘ
country United States ⓘ
developedDrug LOXO-195 ⓘ
LOXO-292 ⓘ
LOXO-305 ⓘ
larotrectinib ⓘ
selpercatinib ⓘ
drugTarget BTK ⓘ
RET alterations ⓘ
TRK fusion proteins ⓘ
focusesOn precision oncology ⓘ
small molecule therapies ⓘ
targeted cancer therapies ⓘ
foundedIn 2013 ⓘ
headquartersLocation Stamford, Connecticut ⓘ
industry biotechnology ⓘ
pharmaceuticals ⓘ
laterHeadquartersLocation Stamford, Connecticut, United States ⓘ
leadProduct larotrectinib ⓘ
leadProductAlsoKnownAs LOXO-101 ⓘ
linked to: LOXO-195
leadProductIndication NTRK gene fusion-positive solid tumors ⓘ
leadProductMarketedName Vitrakvi ⓘ
listedOn NASDAQ ⓘ
notableCollaboration Bayer ⓘ
parentOrganizationAfterAcquisition Eli Lilly and Company ⓘ
regulatoryAgencyApproval U.S. Food and Drug Administration ⓘ
regulatoryApprovalFor larotrectinib ⓘ
regulatoryApprovalYear 2018 ⓘ
regulatoryMilestone first TRK inhibitor approved in the United States ⓘ
researchApproach genomics-driven drug discovery ⓘ
tumor-agnostic therapy development ⓘ
secondMajorProduct selpercatinib ⓘ
secondMajorProductAlsoKnownAs LOXO-292 ⓘ
secondMajorProductIndication RET-altered lung and thyroid cancers ⓘ
secondMajorProductMarketedName Retevmo ⓘ
specializesIn oncogenic driver mutations ⓘ
tumors driven by specific genetic alterations ⓘ
tickerSymbolBeforeAcquisition LOXO ⓘ

How these facts were elicited

Referenced by (10)

Full triples — surface form annotated when it differs from this entity's canonical label.

Eli Lilly and Company → hasSubsidiary → Loxo Oncology (acquired) ⓘ
larotrectinib → developer → Loxo Oncology ⓘ
linked to: Loxo Oncology (acquired)
LOXO-292 → hasDeveloper → Loxo Oncology ⓘ
linked to: Loxo Oncology (acquired)
Vitrakvi → hasDeveloper → Loxo Oncology ⓘ
linked to: Loxo Oncology (acquired)
Joshua Bilenker → founded → Loxo Oncology ⓘ
linked to: Loxo Oncology (acquired)
Joshua Bilenker → employer → Loxo Oncology ⓘ
linked to: Loxo Oncology (acquired)
Keith Flaherty → coFounderOf → Loxo Oncology ⓘ
linked to: Loxo Oncology (acquired)
Keith Flaherty → affiliation → Loxo Oncology ⓘ
linked to: Loxo Oncology (acquired)
LOXO-195 → developedBy → Loxo Oncology ⓘ
linked to: Loxo Oncology (acquired)
LOXO-305 → developer → Loxo Oncology ⓘ
linked to: Loxo Oncology (acquired)